Serum Concentration on Mineral Zinc and Cognitive Changes in Children: a Review


Introduction: Micronutrient deficiencies in children in developing countries remain a public health problem, as they are persistently common. Among them, zinc is an essential trace element and plays a crucial role in biological functions and physiological processes in humans. Disorders of zinc balance during life appear to be an important factor correlated with the development of CNS diseases. This research aimed to conduct a literature review on the proportion of research involving zinc and brain development in children. Methods: A search was performed in the Pubmed, Scorpus, and Web of Science databases, and articles from the last 5 years were retrieved. According to the criteria, 7 articles were chosen to compose this review. Results: 57% revealed that children with ASD have low serum zinc levels, and 29% of the studies found lower plasma zinc levels in children diagnosed with ADHD. Revealing that attention to the levels of zinc in the plasma must be special, since mainly the levels of micronutrients, are decisive for a good biological, physiological, neurobiological, and behavioral development, acting on the personality and formation of the human being. Conclusion: In this perspective, we emphasize the importance of giving greater attention to the serum levels of adequate zinc in the human body, renewing the knowledge that adequate nutrition is of great importance for normal development from pregnancy to aging.

Keywords: Child. Zinc. Brain.

Samillys Valeska Bezerra de França Silva;
Micheline Morgane Figueiredo Costa Souza;
Jéssica Raque de Santana;
José Edvan de Souza Júnior;
José Rodolfo Lopes de Paiva Cavalcanti.

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