Vol 2(3) May-Jun

Prevalence and Associated Factors of Gestational Diabetes Mellitus

Abstract:

Objective: A cross-sectional study was carried out to estimate the prevalence of gestational diabetes mellitus (GDM) in Mossoró/RN and to evaluate the correlation of associated risk factors. Subjects and methods: Pregnant women attended at Brazilian National Health Service between January 2016 and January 2017 were evaluated using a specific questionnaire with demographics and baseline caractheristics and first trimester fasting plasma glucose glycemic (FPG), followed by OGTT 75g schedule between 24 and 28 weeks of gestation. Diagnostic criteria recommended by the IADPSG were used. Results: 166 pregnant women were recruited, with a mean age of 24.7 years, predominance of brown and white races, most with low schooling and low income, 38.5% presenting pre-gestational weight excess. Of the pregnant women with FPG collected in the first trimester, 13.8% had GDM, with a mean FPG 101.2 mg/dL; among 76 patients who completed the evaluation, 04 (5.3%) had a diagnosis of GDM with OGTT 75g, totaling 20 of 76 patients evaluated, with a total prevalence of 26.3%. Direct correlation between age and GDM was observed only in pregnant women diagnosed in the first trimester. No correlation was observed with the other factors evaluated: color, height, income, schooling, history of PCOS and gestational hypertension, family history of DM2, pre-gestational obesity and sedentary lifestyle. Conclusion: a high prevalence of GDM was identified, with a large percentage already identified in the first trimester. Additional studies are needed to better define risk factors in this population, as well as the impact of this early diagnosis on neonatal outcomes.

Keywords: Gestational diabetes. Prevalence. Risk factors.

Authors:
Gilka Firmino Torres Barisic;
Lidia Maria Oliveira Barisic;
Lucas Costa Feitosa Alves;
Stephan Barisic;
Fausto Pierdoná Guzen;
Eudes Euler de Souza Lucena.

Hyptis Suaveolens L. Poit Essential Oil Induces Trophism in Spinal Cord Cells

Abstract:
Spinal cord injury is a source of significant disabilities that needs the combination of different strategies to obtain functional recovery results. In this regard some medicinal plants also have activities in the central nervous system and their essential oils, product of the secondary metabolism, are effective in different disorders of this system. Hyptis suaveolens (L.) Poit (HS) is a plant thatproduces essential oil with antiinflammatory, antioxidant andneuroprotective activity. Thus,this study analyzed the cellularplasticity of spinal cord cells inthe presence of sciatic nerve-conditionedmedium (SNCM) and theaddition of HS essential oil. Cellmorphology was assessed over 96hours, and immunocytochemistryanalyses were conducted for Glialfibrillary acidic protein (GFAP)and Neuronal Nuclear antigen (NeuN). Photomicrographs were made by scanning electron microscopy (SEM). Morphological analysis showed evident trophic development in the groups that received HS essential oil (p<0,05), particularly glial cells, immunoreactivity for GFAP, and NeuN and the plasticity of these cells were confirmed by SEM. This study about the plasticity of spinal cord cells contributes with new possibilities and techniques with essential oils for cell therapy in the presence of SNCM, which promoted neuroprotective action.

Keywords: Spinal Cord Injuries. Neuroprotection. Neurotrophism. Essential oil.

Authors:
Luciana Cristina Borges Fernandes;
Rodrigo Freire Oliveira;
Salvador Viana Junior;
Ianara Mendonça Costa;
Francisca Idalina Neta;
Francisca Overlânia Vieira Lima;
Lucídio Clebeson Oliveira;
Sergio da Silva Bezerra de Menenzes;
Dinalva Brito de Queiroz;
Carlos Iberê Alves Freitas;
Fausto Pierdoná Guzen.

Neural Action Potential Relating to Neural Connectivity Issues on Autism Spectrum Disorder: a Mini Review

Abstract:
Autism Spectrum Disorder (ASD) is a set of neurodevelopmental features which represent limitations for the individual in his/her social, affective and functional life. Previously named as Pervasive Developmental Disorder, nowadays autism is conceived as a spectrum and is a vast fan of manifestations, usually with repetitive behavior, some delay on language acquisition and isolation. The present mini review aims to study ASD starting from the Neural Action Potential as initial element of neural networks, connectivity and relation of the individual with the environment, based on neurosciences, studies that have been published during the last 5 years on PUBMED and Google Scholar databases. Discussion takes place as a theoretical approach to possibilities of construction of those neural connections and its implications to ASD symptoms. It is urgent to spread information about ASD in order to search for better therapy strategies, relation between family and health professional formation centers as well as ameliorate ASD-assistance services.

Keywords: Autism Spectrum Disorder. Neural Action Potential. Autism Neural Connectivity.

Authors:
Amélia Carolina Lopes Fernandes;
Dayane Pessoa de Araújo;
Fausto Pierdoná Guzen;
Francisca Patrícia Barreto de Carvalho;
José Rodolfo Lopes de Paiva Cavalcanti;
Jussara Rodrigues de Alcantara;
Lisandra Alves da Silva;
Lucidio Clebeson de Oliveira;
Paulo Leonardo Araújo de Góis Morais.

Incidene of Self-Medication Amongst Elderly People

Abstract:
The work aims to know the factors that contribute to the self-medication of the elderly people, as well as to characterize the main risks of self-medication in the elder. This is an exploratory descriptive research with a quantitative approach. The study sample consisted of 144 elderly people from the municipality of Morada Nova in Ceará. Data were expressed as mean, standard deviation, minimum and maximum values, as well as simple frequency and percentage calculated using the 20.0 version of SPSS statistical software (Statistical Package for Social Sciences). It was found that 88.2% of the elderly people have had medication for more than a year, 68% have had more than three medications daily, 42.2% of the interviewees had their last appointment less than a month before, 77.8% stated that they did not have help with the use of medicines. In this sense, it was evident that the practice of self-medication is frequent in the elderly people, which reflects the need to work with health promotion groups in order to reduce possible damage caused by the inappropriate use of medicines.

Keywords: Elderly. Self-medication. Nursing.

Authors:
Thaisa Christina Reinaldo Monteiro;
Amélia Carolina Lopes Fernandes;
Dayane Pessoa de Araújo;
José Rodolfo Lopes de Paiva Cavalcanti;
Francisca Patrícia Barreto de Carvalho;
Ana Cristina Arrais;
Eudes Euler de Souza Lucena;
Lucidio Clebeson de Oliveira.

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