Author page: JPCBS

Herbs as an Alternative Treatment for Climateric Symptoms

Abstract:

There is a period in the life of the woman marked by the transition from the reproductive to the non-reproductive phase a woman’s life, beginning with the decline of the ovarian function and the announcement of the menopause, to this period is called Climaterium. Conventional treatments based on hormone replacement therapy (synthetic hormones) have shown a decline in the relation of this to the development of diseases such as breast cancer, so there was a greater search for new forms of treatment, such as the use of phytohormones that have propagated in recente times in Brazil. Considering the above and the research carried out through a questionnaire applied to climacteric women in the city of Mossoro – RN, and through bibliographic reviews, this work aims at the development of a compound based on medicinal herbs marketed in the city of Mossoró that have properties the most recurrent symptoms of the climacteric, and with that providing an improvement in the quality of life of these women.

Keywords: Herbs;  Climateric; Alternative treatment; Women health.

Authors:
Alan Victor Freitas Malveira;
Danielly Da Silva Rego;
Driely Dandary Soares Mendes;
Gislaine Thais Rebouças De Freitas;
Guilherme Oliveira Da Costa;
Lucas Emmanuel Rocha de Moura Marques;
Yanna Gabriele Guimarães Lopes and
Gabriella Mendes Duarte.

Cytoarchitectural Characterization of the Medial Geniculated Body of Young Wistar Rats (Rattus Norvegicus) Through Immunohistochemistry for S100B

Abstract:

Several molecular, cytoarchitectural and neurochemical works study the Medial Geniculate Body (MGB), a thalamus structure related to the auditory pathway. This region is composed of several nuclei of neurons, mainly of retransmission to the auditory cortex, in addition to astrocytes and axon fibers. In order to make MGB’s histophysiological knowledge solid, several astrocyte markers are commonly used, such as GFAP, S100B and metabolic enzyme aldehyde dehydrogenase 1 (Al- dh1L1). We studied the pattern of distribution and immunoreactivityfor S100B in the MGB of young wistar rats and we were able not only to delimit and characterize the topography as a whole of this area, but also to obtain the subdivision of some sub-regions. In this sense, we found that immunohistochemistry against S100, classically, can be used to characterize the MGB, as our results indicated that it is a reliable marker for cytoarchitectonic studies in this área in young rats.

Keywords: Astrocytes; Calcium Binding Proteins; Medial Geniculate Body; Protein S100B.

Authors:
Leandro Diniz da Silva;
Gabriel Sousa da Rocha;
Karina Maia Paiva;
Rodrigo Freire Oliveira;
Kalina Fernandes Freire;
Acydália Madruga de Mendonça Florêncio de Melo;
Ana Cristina Arrais;
Lucidio Clebeson de Oliveira;
Paulo Leonardo Araújo de Gois Morais;
Lívia Helena de Morais Freitas Melo and
José Rodolfo Lopes de Paiva Cavalcanti

Prevalence and Associated Factors of Gestational Diabetes Mellitus

Abstract:

Objective: A cross-sectional study was carried out to estimate the prevalence of gestational diabetes mellitus (GDM) in Mossoró/RN and to evaluate the correlation of associated risk factors. Subjects and methods: Pregnant women attended at Brazilian National Health Service between January 2016 and January 2017 were evaluated using a specific questionnaire with demographics and baseline caractheristics and first trimester fasting plasma glucose glycemic (FPG), followed by OGTT 75g schedule between 24 and 28 weeks of gestation. Diagnostic criteria recommended by the IADPSG were used. Results: 166 pregnant women were recruited, with a mean age of 24.7 years, predominance of brown and white races, most with low schooling and low income, 38.5% presenting pre-gestational weight excess. Of the pregnant women with FPG collected in the first trimester, 13.8% had GDM, with a mean FPG 101.2 mg/dL; among 76 patients who completed the evaluation, 04 (5.3%) had a diagnosis of GDM with OGTT 75g, totaling 20 of 76 patients evaluated, with a total prevalence of 26.3%. Direct correlation between age and GDM was observed only in pregnant women diagnosed in the first trimester. No correlation was observed with the other factors evaluated: color, height, income, schooling, history of PCOS and gestational hypertension, family history of DM2, pre-gestational obesity and sedentary lifestyle. Conclusion: a high prevalence of GDM was identified, with a large percentage already identified in the first trimester. Additional studies are needed to better define risk factors in this population, as well as the impact of this early diagnosis on neonatal outcomes.

Keywords: Gestational diabetes. Prevalence. Risk factors.

Authors:
Gilka Firmino Torres Barisic;
Lidia Maria Oliveira Barisic;
Lucas Costa Feitosa Alves;
Stephan Barisic;
Fausto Pierdoná Guzen;
Eudes Euler de Souza Lucena.

Hyptis Suaveolens L. Poit Essential Oil Induces Trophism in Spinal Cord Cells

Abstract:
Spinal cord injury is a source of significant disabilities that needs the combination of different strategies to obtain functional recovery results. In this regard some medicinal plants also have activities in the central nervous system and their essential oils, product of the secondary metabolism, are effective in different disorders of this system. Hyptis suaveolens (L.) Poit (HS) is a plant thatproduces essential oil with antiinflammatory, antioxidant andneuroprotective activity. Thus,this study analyzed the cellularplasticity of spinal cord cells inthe presence of sciatic nerve-conditionedmedium (SNCM) and theaddition of HS essential oil. Cellmorphology was assessed over 96hours, and immunocytochemistryanalyses were conducted for Glialfibrillary acidic protein (GFAP)and Neuronal Nuclear antigen (NeuN). Photomicrographs were made by scanning electron microscopy (SEM). Morphological analysis showed evident trophic development in the groups that received HS essential oil (p<0,05), particularly glial cells, immunoreactivity for GFAP, and NeuN and the plasticity of these cells were confirmed by SEM. This study about the plasticity of spinal cord cells contributes with new possibilities and techniques with essential oils for cell therapy in the presence of SNCM, which promoted neuroprotective action.

Keywords: Spinal Cord Injuries. Neuroprotection. Neurotrophism. Essential oil.

Authors:
Luciana Cristina Borges Fernandes;
Rodrigo Freire Oliveira;
Salvador Viana Junior;
Ianara Mendonça Costa;
Francisca Idalina Neta;
Francisca Overlânia Vieira Lima;
Lucídio Clebeson Oliveira;
Sergio da Silva Bezerra de Menenzes;
Dinalva Brito de Queiroz;
Carlos Iberê Alves Freitas;
Fausto Pierdoná Guzen.

Neural Action Potential Relating to Neural Connectivity Issues on Autism Spectrum Disorder: a Mini Review

Abstract:
Autism Spectrum Disorder (ASD) is a set of neurodevelopmental features which represent limitations for the individual in his/her social, affective and functional life. Previously named as Pervasive Developmental Disorder, nowadays autism is conceived as a spectrum and is a vast fan of manifestations, usually with repetitive behavior, some delay on language acquisition and isolation. The present mini review aims to study ASD starting from the Neural Action Potential as initial element of neural networks, connectivity and relation of the individual with the environment, based on neurosciences, studies that have been published during the last 5 years on PUBMED and Google Scholar databases. Discussion takes place as a theoretical approach to possibilities of construction of those neural connections and its implications to ASD symptoms. It is urgent to spread information about ASD in order to search for better therapy strategies, relation between family and health professional formation centers as well as ameliorate ASD-assistance services.

Keywords: Autism Spectrum Disorder. Neural Action Potential. Autism Neural Connectivity.

Authors:
Amélia Carolina Lopes Fernandes;
Dayane Pessoa de Araújo;
Fausto Pierdoná Guzen;
Francisca Patrícia Barreto de Carvalho;
José Rodolfo Lopes de Paiva Cavalcanti;
Jussara Rodrigues de Alcantara;
Lisandra Alves da Silva;
Lucidio Clebeson de Oliveira;
Paulo Leonardo Araújo de Góis Morais.

Incidene of Self-Medication Amongst Elderly People

Abstract:
The work aims to know the factors that contribute to the self-medication of the elderly people, as well as to characterize the main risks of self-medication in the elder. This is an exploratory descriptive research with a quantitative approach. The study sample consisted of 144 elderly people from the municipality of Morada Nova in Ceará. Data were expressed as mean, standard deviation, minimum and maximum values, as well as simple frequency and percentage calculated using the 20.0 version of SPSS statistical software (Statistical Package for Social Sciences). It was found that 88.2% of the elderly people have had medication for more than a year, 68% have had more than three medications daily, 42.2% of the interviewees had their last appointment less than a month before, 77.8% stated that they did not have help with the use of medicines. In this sense, it was evident that the practice of self-medication is frequent in the elderly people, which reflects the need to work with health promotion groups in order to reduce possible damage caused by the inappropriate use of medicines.

Keywords: Elderly. Self-medication. Nursing.

Authors:
Thaisa Christina Reinaldo Monteiro;
Amélia Carolina Lopes Fernandes;
Dayane Pessoa de Araújo;
José Rodolfo Lopes de Paiva Cavalcanti;
Francisca Patrícia Barreto de Carvalho;
Ana Cristina Arrais;
Eudes Euler de Souza Lucena;
Lucidio Clebeson de Oliveira.

Bioactive and Nutraceutical Properties of Mushrooms in Body Aesthetic

Abstract:

Mushrooms are fruiting bodies of fungi, some species of edible mushrooms being used as part of traditional diets, such as a Mediterranean. In this sense, edible mushrooms have emerged as a viable alternative increasingly common in the Brazilian table due to their nutritional properties. This article aimed to evaluate the benefits of the bioactive and nutritional properties of mushrooms on body aesthetics. This study consists of a literature review where an electronic search was performed in the United States: PubMed, Science Direct, Cochrane Library, Scientific Electronic Library, Online Databases (SciELO), Scopus, Web of Science, Medline via Proquest and Capes Periodicals covering the years 1989-2019, using the terms “Nutrient Mushrooms” “Mushrooms, Vitamins, Food Supplementation” “Mushrooms and Nutrition and Micronutrients” “Mushrooms and Nutrition and Macronutrients”“Nutrient Mushrooms and Nutraceuticals “Mushroom and aesthetics” Mushroom and antioxidant. Mushrooms are rich in proteins with good bioavailability, low lipid content and excellent fiber source that can be used as nutritional, advanced for their bioactive compounds, polyphenols and other biological compounds that perform body aesthetic activities.

Keywords: Mushrooms. Macronutrients. Micronutrients. Body Aesthetics.

Authors:
Vinicius Umbelino de Freitas;
Anna Ingrid Soares de Sousa Espindola;
Catarina Melissa Carlos de Castro;
Fernando Liberalino Fernandes ;
Ninodja Kadja Peixoto Nóbrega;
Jenifer Kristina Alves Almeida;
Fausto Pierdoná Guzen.

Benefits of Supplementation with Herbal Medicines in Anabolic Hormone Replacement Related to Aging

Abstract:

Exercise can be carried out according to the morphological and physiological changes of the living organism over time. The increase in life expectancy is also an achievement along with functional decline and increased disease are observed. Aging in a healthy way for a general well-being, however, when aging is not successful, the elderly have a great tendency towards a functional, cognitive and other diseases, generating the total dependence of basic activities, thus determining the need care. The present article had the objective of supplementation with phytotherapics in the anabolic hormone replacement related to aging. The study was based on the literature review, and a case study was done in the United States. Library of Medicine, Pub Direct, Science Direct, Cochrane Library, Electronic Scientific Library, Online Databases (SciELO), Scopus, Web of Science, Medline via Proquest and Periodics capturing the years between 2007 and 2019, using the terms of reference “Aging and Metabolic Alterations” “Aging and Phytotherapics” “Aging and Tribulus terrestris” “Aging and Maca Peruvian” “Aging and Ginseng”, in addition we related the term hormone with each phytotherapeutic mentioned. They observe that the herbal remedies Tribulus terrestris, Maca peruana and Ginseng possess in their combination with the chemistry, anabolic, being thus, a supplementation with these products can allow an anabolic hormonal balance, generating the effect in the levels of catabolic hormones, providing a better This topic was extracted from population longevity.

Keywords: Aging. Anabolic Hormones. Herbal Medicine. Supplementation

Authors:
Anna Ingrid Soares de Sousa Espindola;
Bruna Stefany Souza Sabino;
Catarina Melissa Carlos de Castro Duarte;
Gabrielle Tereza Santos de Souza;
Marina Geovanni Marques de Santana;
Ninodja Kadja Peixoto Nóbrega;
Pedro Henrique Bezerra Gomes;
Ana Katarina Dias de Oliveira;
Fausto Pierdoná Guzen.

Serum Concentration on Mineral Zinc and Cognitive Changes in Children: a Review

Abstract:

Introduction: Micronutrient deficiencies in children in developing countries remain a public health problem, as they are persistently common. Among them, zinc is an essential trace element and plays a crucial role in biological functions and physiological processes in humans. Disorders of zinc balance during life appear to be an important factor correlated with the development of CNS diseases. This research aimed to conduct a literature review on the proportion of research involving zinc and brain development in children. Methods: A search was performed in the Pubmed, Scorpus, and Web of Science databases, and articles from the last 5 years were retrieved. According to the criteria, 7 articles were chosen to compose this review. Results: 57% revealed that children with ASD have low serum zinc levels, and 29% of the studies found lower plasma zinc levels in children diagnosed with ADHD. Revealing that attention to the levels of zinc in the plasma must be special, since mainly the levels of micronutrients, are decisive for a good biological, physiological, neurobiological, and behavioral development, acting on the personality and formation of the human being. Conclusion: In this perspective, we emphasize the importance of giving greater attention to the serum levels of adequate zinc in the human body, renewing the knowledge that adequate nutrition is of great importance for normal development from pregnancy to aging.

Keywords: Child. Zinc. Brain.

Authors:
Samillys Valeska Bezerra de França Silva;
Micheline Morgane Figueiredo Costa Souza;
Jéssica Raque de Santana;
José Edvan de Souza Júnior;
José Rodolfo Lopes de Paiva Cavalcanti.

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