Author page: JPCBS

Dietotherapy in Health Promotion and Recovery in Seropositive Patients

Abstract:
Introduction: Nutritional guidance Works as a gradual process of diet adhering, whereby human immunodeficiency virus patients are advised to take responsibility and become aware of the food relationship in the treatment itself. Thus, it is possible to promote a better quality of life for these patients. Objectives: Address the need for nutritional care and follow-up of seropositive human immunodeficiency patients. Methods: Consists of a literature review, where an electronic research was carried out in the databases: PubMed, SciELO, LILACS, Capes Journal Portal, as well as printed literature, covering the years between 1995 and 2020. Results: Nutritional assessment of seropositive patients should be comprehensive and judicious, including the detection of symptoms associated with viral infection and anthropometric and biological parameters. From this, nutritional risks are identified and associated with gastrointestinal, autoimune and opportunistic pathologies. It is essential that HIV-patients receive nutritional therapy early and continuously, aiming at food reeducation and adequate supply of macros and micronutrients. Conclusion: Since there is no pre-established definitive nutritional assessment or therapy for HIV-patients, the main purpose of treatment is the recovery of nutritional status as well as its immunological status, thus promoting necessary conditions for body homeostasis and disease remission.

Keywords: Nutritional Assessment; Supplementation; Immunodeficiency.

Authors:
Marcos Vinícius Luz de Oliveira;
Natália Chagas de Oliveira;
Francisco Sérvulo de Oliveira Carvalho;
Lara Barbosa de Souza.

Physiological and Clinical Aspects of Eletrical Synapse: Emphasis of the Connexin 36

Abstract:
The aim of this review is to gather recente findings from the literature on how electrical synapses act and how changes in their structure, with emphasis on conexin 36 influences clinical aspects. Research studies have been selected based on research topics found in globally recognized databases such as Web of Science, PubMed, Springer and Scopus from 2009 to date and ranked by relevance. Previously, it was believed that brain functioning required only electrical circuits for decision making. However, John Eccles has proven the predominance of chemical synapses in the nervous system; This hypothesis that led to discrediting the functionality of electrical synapses. However, several studies have described the structure of the gap junctions and the mechanisms of the electrical synapse, which occurs through two mechanisms: through low resistance interneuronal pathways through the communicating junctions and through extracellular electric fields generated by nerve cell activity. Therefore, it is a fact that this form of cellular communication has greater clinical applicability such as synchronization of electrical transmission in different neural groups. The prime example of this applicability is the existence of mixed synapses. This feature may be the key point for clarifying the genesis of various pathologies associated with cognitive disorders, learning and memory deficits.

Keywords: Electrical Synapses; Connexin36; Neuronal Gap Junctions.

Authors:
Hosana Mirelle Goes e Silva Costa;
Paulo Leonardo Araújo de Góis Morais;
Débora Lopes Silva de Souza;
Claudio Lopes de Vasconcelos;
Dayane Pessoa de Araújo;
Lucidio Clebeson de Oliveira;
José Edvan de Souza Júnior;
Fausto Pierdoná Guzen;
José Rodolfo Lopes de Paiva Cavalcanti.

Herbs as an Alternative Treatment for Climateric Symptoms

Abstract:

There is a period in the life of the woman marked by the transition from the reproductive to the non-reproductive phase a woman’s life, beginning with the decline of the ovarian function and the announcement of the menopause, to this period is called Climaterium. Conventional treatments based on hormone replacement therapy (synthetic hormones) have shown a decline in the relation of this to the development of diseases such as breast cancer, so there was a greater search for new forms of treatment, such as the use of phytohormones that have propagated in recente times in Brazil. Considering the above and the research carried out through a questionnaire applied to climacteric women in the city of Mossoro – RN, and through bibliographic reviews, this work aims at the development of a compound based on medicinal herbs marketed in the city of Mossoró that have properties the most recurrent symptoms of the climacteric, and with that providing an improvement in the quality of life of these women.

Keywords: Herbs;  Climateric; Alternative treatment; Women health.

Authors:
Alan Victor Freitas Malveira;
Danielly Da Silva Rego;
Driely Dandary Soares Mendes;
Gislaine Thais Rebouças De Freitas;
Guilherme Oliveira Da Costa;
Lucas Emmanuel Rocha de Moura Marques;
Yanna Gabriele Guimarães Lopes and
Gabriella Mendes Duarte.

Cytoarchitectural Characterization of the Medial Geniculated Body of Young Wistar Rats (Rattus Norvegicus) Through Immunohistochemistry for S100B

Abstract:

Several molecular, cytoarchitectural and neurochemical works study the Medial Geniculate Body (MGB), a thalamus structure related to the auditory pathway. This region is composed of several nuclei of neurons, mainly of retransmission to the auditory cortex, in addition to astrocytes and axon fibers. In order to make MGB’s histophysiological knowledge solid, several astrocyte markers are commonly used, such as GFAP, S100B and metabolic enzyme aldehyde dehydrogenase 1 (Al- dh1L1). We studied the pattern of distribution and immunoreactivityfor S100B in the MGB of young wistar rats and we were able not only to delimit and characterize the topography as a whole of this area, but also to obtain the subdivision of some sub-regions. In this sense, we found that immunohistochemistry against S100, classically, can be used to characterize the MGB, as our results indicated that it is a reliable marker for cytoarchitectonic studies in this área in young rats.

Keywords: Astrocytes; Calcium Binding Proteins; Medial Geniculate Body; Protein S100B.

Authors:
Leandro Diniz da Silva;
Gabriel Sousa da Rocha;
Karina Maia Paiva;
Rodrigo Freire Oliveira;
Kalina Fernandes Freire;
Acydália Madruga de Mendonça Florêncio de Melo;
Ana Cristina Arrais;
Lucidio Clebeson de Oliveira;
Paulo Leonardo Araújo de Gois Morais;
Lívia Helena de Morais Freitas Melo and
José Rodolfo Lopes de Paiva Cavalcanti

Prevalence and Associated Factors of Gestational Diabetes Mellitus

Abstract:

Objective: A cross-sectional study was carried out to estimate the prevalence of gestational diabetes mellitus (GDM) in Mossoró/RN and to evaluate the correlation of associated risk factors. Subjects and methods: Pregnant women attended at Brazilian National Health Service between January 2016 and January 2017 were evaluated using a specific questionnaire with demographics and baseline caractheristics and first trimester fasting plasma glucose glycemic (FPG), followed by OGTT 75g schedule between 24 and 28 weeks of gestation. Diagnostic criteria recommended by the IADPSG were used. Results: 166 pregnant women were recruited, with a mean age of 24.7 years, predominance of brown and white races, most with low schooling and low income, 38.5% presenting pre-gestational weight excess. Of the pregnant women with FPG collected in the first trimester, 13.8% had GDM, with a mean FPG 101.2 mg/dL; among 76 patients who completed the evaluation, 04 (5.3%) had a diagnosis of GDM with OGTT 75g, totaling 20 of 76 patients evaluated, with a total prevalence of 26.3%. Direct correlation between age and GDM was observed only in pregnant women diagnosed in the first trimester. No correlation was observed with the other factors evaluated: color, height, income, schooling, history of PCOS and gestational hypertension, family history of DM2, pre-gestational obesity and sedentary lifestyle. Conclusion: a high prevalence of GDM was identified, with a large percentage already identified in the first trimester. Additional studies are needed to better define risk factors in this population, as well as the impact of this early diagnosis on neonatal outcomes.

Keywords: Gestational diabetes. Prevalence. Risk factors.

Authors:
Gilka Firmino Torres Barisic;
Lidia Maria Oliveira Barisic;
Lucas Costa Feitosa Alves;
Stephan Barisic;
Fausto Pierdoná Guzen;
Eudes Euler de Souza Lucena.

Hyptis Suaveolens L. Poit Essential Oil Induces Trophism in Spinal Cord Cells

Abstract:
Spinal cord injury is a source of significant disabilities that needs the combination of different strategies to obtain functional recovery results. In this regard some medicinal plants also have activities in the central nervous system and their essential oils, product of the secondary metabolism, are effective in different disorders of this system. Hyptis suaveolens (L.) Poit (HS) is a plant thatproduces essential oil with antiinflammatory, antioxidant andneuroprotective activity. Thus,this study analyzed the cellularplasticity of spinal cord cells inthe presence of sciatic nerve-conditionedmedium (SNCM) and theaddition of HS essential oil. Cellmorphology was assessed over 96hours, and immunocytochemistryanalyses were conducted for Glialfibrillary acidic protein (GFAP)and Neuronal Nuclear antigen (NeuN). Photomicrographs were made by scanning electron microscopy (SEM). Morphological analysis showed evident trophic development in the groups that received HS essential oil (p<0,05), particularly glial cells, immunoreactivity for GFAP, and NeuN and the plasticity of these cells were confirmed by SEM. This study about the plasticity of spinal cord cells contributes with new possibilities and techniques with essential oils for cell therapy in the presence of SNCM, which promoted neuroprotective action.

Keywords: Spinal Cord Injuries. Neuroprotection. Neurotrophism. Essential oil.

Authors:
Luciana Cristina Borges Fernandes;
Rodrigo Freire Oliveira;
Salvador Viana Junior;
Ianara Mendonça Costa;
Francisca Idalina Neta;
Francisca Overlânia Vieira Lima;
Lucídio Clebeson Oliveira;
Sergio da Silva Bezerra de Menenzes;
Dinalva Brito de Queiroz;
Carlos Iberê Alves Freitas;
Fausto Pierdoná Guzen.

Neural Action Potential Relating to Neural Connectivity Issues on Autism Spectrum Disorder: a Mini Review

Abstract:
Autism Spectrum Disorder (ASD) is a set of neurodevelopmental features which represent limitations for the individual in his/her social, affective and functional life. Previously named as Pervasive Developmental Disorder, nowadays autism is conceived as a spectrum and is a vast fan of manifestations, usually with repetitive behavior, some delay on language acquisition and isolation. The present mini review aims to study ASD starting from the Neural Action Potential as initial element of neural networks, connectivity and relation of the individual with the environment, based on neurosciences, studies that have been published during the last 5 years on PUBMED and Google Scholar databases. Discussion takes place as a theoretical approach to possibilities of construction of those neural connections and its implications to ASD symptoms. It is urgent to spread information about ASD in order to search for better therapy strategies, relation between family and health professional formation centers as well as ameliorate ASD-assistance services.

Keywords: Autism Spectrum Disorder. Neural Action Potential. Autism Neural Connectivity.

Authors:
Amélia Carolina Lopes Fernandes;
Dayane Pessoa de Araújo;
Fausto Pierdoná Guzen;
Francisca Patrícia Barreto de Carvalho;
José Rodolfo Lopes de Paiva Cavalcanti;
Jussara Rodrigues de Alcantara;
Lisandra Alves da Silva;
Lucidio Clebeson de Oliveira;
Paulo Leonardo Araújo de Góis Morais.

Incidene of Self-Medication Amongst Elderly People

Abstract:
The work aims to know the factors that contribute to the self-medication of the elderly people, as well as to characterize the main risks of self-medication in the elder. This is an exploratory descriptive research with a quantitative approach. The study sample consisted of 144 elderly people from the municipality of Morada Nova in Ceará. Data were expressed as mean, standard deviation, minimum and maximum values, as well as simple frequency and percentage calculated using the 20.0 version of SPSS statistical software (Statistical Package for Social Sciences). It was found that 88.2% of the elderly people have had medication for more than a year, 68% have had more than three medications daily, 42.2% of the interviewees had their last appointment less than a month before, 77.8% stated that they did not have help with the use of medicines. In this sense, it was evident that the practice of self-medication is frequent in the elderly people, which reflects the need to work with health promotion groups in order to reduce possible damage caused by the inappropriate use of medicines.

Keywords: Elderly. Self-medication. Nursing.

Authors:
Thaisa Christina Reinaldo Monteiro;
Amélia Carolina Lopes Fernandes;
Dayane Pessoa de Araújo;
José Rodolfo Lopes de Paiva Cavalcanti;
Francisca Patrícia Barreto de Carvalho;
Ana Cristina Arrais;
Eudes Euler de Souza Lucena;
Lucidio Clebeson de Oliveira.

Bioactive and Nutraceutical Properties of Mushrooms in Body Aesthetic

Abstract:

Mushrooms are fruiting bodies of fungi, some species of edible mushrooms being used as part of traditional diets, such as a Mediterranean. In this sense, edible mushrooms have emerged as a viable alternative increasingly common in the Brazilian table due to their nutritional properties. This article aimed to evaluate the benefits of the bioactive and nutritional properties of mushrooms on body aesthetics. This study consists of a literature review where an electronic search was performed in the United States: PubMed, Science Direct, Cochrane Library, Scientific Electronic Library, Online Databases (SciELO), Scopus, Web of Science, Medline via Proquest and Capes Periodicals covering the years 1989-2019, using the terms “Nutrient Mushrooms” “Mushrooms, Vitamins, Food Supplementation” “Mushrooms and Nutrition and Micronutrients” “Mushrooms and Nutrition and Macronutrients”“Nutrient Mushrooms and Nutraceuticals “Mushroom and aesthetics” Mushroom and antioxidant. Mushrooms are rich in proteins with good bioavailability, low lipid content and excellent fiber source that can be used as nutritional, advanced for their bioactive compounds, polyphenols and other biological compounds that perform body aesthetic activities.

Keywords: Mushrooms. Macronutrients. Micronutrients. Body Aesthetics.

Authors:
Vinicius Umbelino de Freitas;
Anna Ingrid Soares de Sousa Espindola;
Catarina Melissa Carlos de Castro;
Fernando Liberalino Fernandes ;
Ninodja Kadja Peixoto Nóbrega;
Jenifer Kristina Alves Almeida;
Fausto Pierdoná Guzen.

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